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Skin-brain axis? Scientists find mental health link hiding in your skin

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In a pioneering study published on May 27, 2025, in the British Journal of Dermatology, Unilever scientists, in collaboration with the University of Liverpool's Microbiome Innovation Centre and Brain & Behaviour Lab, have identified a significant association between the skin microbiome and psychological wellbeing. 

The research focused on the presence of Cutibacterium, a beneficial skin bacterium, across various body sites including the face, scalp, forearm, and underarm. Findings revealed that higher concentrations of Cutibacterium, particularly on the face and underarm, correlated with lower stress levels and improved mood among participants. 

This study introduces the concept of the "skin-brain axis," suggesting that the skin's microbial composition may influence mental health, paralleling the well-established gut-brain axis. Jason Harcup, Unilever's Chief R&D Officer for Beauty & Wellbeing, emphasized the potential of these findings to revolutionize skincare approaches, stating that understanding the skin microbiome's role could lead to products that support both skin health and psychological wellbeing. 

With over 100 microbiome-related patents and one of the world's largest skin microbiome databases, Unilever's research underscores the growing importance of holistic approaches in personal care, bridging the gap between physical and mental health.

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